262 research outputs found

    A Review of the Reorganization of School Districts in the State of Washington

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    The vast number of school districts in Washington State has been greatly reduced over a period of years by various consolidation and reorganization laws. These laws cover a span of over sixty years, and many revisions were innovated during that time. An attempt shall be made to expose the reasons why school districts have been reorganized with a short historical background which ultimately affected consolidation. The basic or main laws governing reorganization shall be written in sequential order from 1903 to 1957

    Transition to adulthood for homeless adolescents

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    Education plays a critical role in how adolescents mature into adults. A vulnerable, and often forgotten, sub-population of the poor is homeless youth, for whom lack of a stable or adequate residence creates a unique set of educational barriers. The Center for Higher Education Policy Analysis (CHEPA) spent 18 months documenting the experiences of homeless adolescents in Los Angeles, deriving data from 123 interviews with homeless adolescents between the ages of 14 and 19, and an additional 45 interviews with shelter staff, social workers, parents, teachers, and school district administrators. Follow-up interviews were conducted with 30 of the youth to understand their experiences in greater depth. Over 400 hours were dedicated to observing the daily lives of homeless youth. The project had two primary goals: (1) To give a voice to homeless youth who are frequently powerless and invisible; and (2) To initiate a dialog with policymakers and practitioners concerning the improvement of educational policy as it pertains to homeless youth. The following research questions framed the analysis: (1) What are the lives of homeless adolescents like? (2) How do homeless youth conceptualize themselves? (3) How do they spend their time? (4) How do they negotiate educational and social barriers? (5) How do they create support systems in and out of school? and (6) What are the different factors they prioritize as crucial to their development? The authors conclude that the current educational system is either irrelevant or hostile to the daily needs of homeless youth. Based on study findings, the authors suggest that policy conversation needs to turn towards addressing specific educational needs to prevent youth from being trapped in a cycle of homelessness. The creation of alternative educational opportunities, mentoring programs, and closer working relationships between shelters and schools warrants greater public discussion on federal, state, and local levels. (Contains 5 boxes and 1 table.) [This research was supported by the John Randolph Haynes and Dora Haynes Foundation.]https://scholarlycommons.pacific.edu/ed-facbooks/1005/thumbnail.jp

    The Timing of Strike-Slip Deformation Along the Storstrþmmen Shear Zone, Greenland Caledonides: U–Pb Zircon and Titanite Geochronology

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    The StorstrĂžmmen shear zone (SSZ) in the Greenland Caledonides is widely interpreted to have formed in a transpressional regime during sinistral, oblique collision between Baltica and Laurentia in the Silurian to Devonian. New mapping of the SSZ at Sanddal documents a 100 m thick, greenschistfacies mylonite zone cutting the eclogite to amphibolite-facies gneiss complex. We present U–Pb ion probe geochronology on zircon and titanite from a variety of lithologies that shows the SSZ was active from late Devonian to the Carboniferous (at least until 350 Ma). The age of thrusting in the foreland is not well known, but must be younger than the age of eclogite-facies metamorphism at ~400 Ma. It is, therefore, possible that contraction is the same age as strike-slip motion, and that transpression is a viable model. The timing of the SSZ is synchronous with dextral strike-slip displacement on the Germania Land deformation zone. Simultaneous displacement on sinistral and dextral, conjugate shear zones suggests that the SSZ is part of a strikeslip fault system that led to lateral escape of material northward (present day coordinates) during the waning stages of plate convergence between Laurentia and Baltica.SOMMAIRELa zone de cisaillement de StorstrĂžmmen (SSZ) dans les CalĂ©donides du Groenland est gĂ©nĂ©ralement comprise comme ayant Ă©tĂ© formĂ©e durant un rĂ©gime de transpression sĂ©nestre lors de la collision oblique entre Baltica et Laurentie, du Silurien au DĂ©vonien.  Une nouvelle cartographie de la SSZ Ă  Sanddal dĂ©crit une zone de 100 m d’épaisseur de mylonite au faciĂšs des schistes verts qui recoupe un complexe de gneiss au faciĂšs Ă©clogite Ă  amphibolite.  Notre analyse gĂ©ochronologique par sonde ionique U-Pb sur zircon et titanite sur diverses lithologies, montre que la SSZ a Ă©tĂ© active de la fin du DĂ©vonien jusqu’au CarbonifĂšre (au moins jusqu’à 350 Ma).  L’ñge du chevauchement dans l’avant-pays n’est pas bien connue, mais il doit ĂȘtre plus jeune que le mĂ©tamorphisme au faciĂšs d’éclogite Ă  ~400 Ma.  Il est donc possible que la contraction soit du mĂȘme Ăąge que le mouvement de coulissage, et que la transpression soit un modĂšle viable.  La chronologie de la SSZ est synchrone au mouvement de coulissage dextre de la zone de dĂ©formation de Germania Land.  Les dĂ©placements simultanĂ©s, sĂ©nestre et dextre, sur des zones de cisaillement conjuguĂ©es permettent de penser que la SSZ fait partie d’un systĂšme de dĂ©crochement qui a engendrĂ© une Ă©jection latĂ©rale de matĂ©riau vers le nord (selon les coordonnĂ©es actuelles) durant les stades de convergence des plaques Laurentie et Baltica

    Part A: Cirrus ice crystal nucleation and growth. Part B: Automated analysis of aircraft ice particle data

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    Specific measurement of cirrus crystals by aircraft and temperature modified CN are used to specify measurements necessary to provide a basis for a conceptual model of cirrus particle formation. Key to this is the ability to measure the complete spectrum of particles at cirrus levels. The most difficult regions for such measurement is from a few to 100 microns, and uses a replicator. The details of the system to automate replicator data analysis are given, together with an example case study of the system provided from a cirrus cloud in FIRE 2, with particles detectable by replicator and FSSP, but not 2DC

    Assessing the impact of different penalty factors of the Bayesian reconstruction algorithm Q.Clear on in vivo low count kinetic analysis of [11C]PHNO brain PET-MR studies

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    INTRODUCTION: Q.Clear is a Bayesian penalised likelihood (BPL) reconstruction algorithm available on General Electric (GE) Positron Emission Tomography (PET)-Computed Tomography (CT) and PET-Magnetic Resonance (MR) scanners. This algorithm is regulated by a ÎČ value which acts as a noise penalisation factor and yields improvements in signal to noise ratio (SNR) in clinical scans, and in contrast recovery and spatial resolution in phantom studies. However, its performance in human brain imaging studies remains to be evaluated in depth. This pilot study aims to investigate the impact of Q.Clear reconstruction methods using different ÎČ value versus ordered subset expectation maximization (OSEM) on brain kinetic modelling analysis of low count brain images acquired in the PET-MR. METHODS: Six [(11)C]PHNO PET-MR brain datasets were reconstructed with Q.Clear with ÎČ100–1000 (in increments of 100) and OSEM. The binding potential relative to non-displaceable volume (BP(ND)) were obtained for the Substantia Nigra (SN), Striatum (St), Globus Pallidus (GP), Thalamus (Th), Caudate (Cd) and Putamen (Pt), using the MIAKATℱ software. Intraclass correlation coefficients (ICC), repeatability coefficients (RC), coefficients of variation (CV) and bias from Bland–Altman plots were reported. Statistical analysis was conducted using a 2-way ANOVA model with correction for multiple comparisons. RESULTS: When comparing a standard OSEM reconstruction of 6 iterations/16 subsets and 5 mm filter with Q.Clear with different ÎČ values under low counts, the bias and RC were lower for Q.Clear with ÎČ100 for the SN (RC = 2.17), Th (RC = 0.08) and GP (RC = 0.22) and with ÎČ200 for the St (RC = 0.14), Cd (RC = 0.18)and Pt (RC = 0.10). The p-values in the 2-way ANOVA model corroborate these findings. ICC values obtained for Th, St, GP, Pt and Cd demonstrate good reliability (0.87, 0.99, 0.96, 0.99 and 0.96, respectively). For the SN, ICC values demonstrate poor reliability (0.43). CONCLUSION: BP(ND) results obtained from quantitative low count brain PET studies using [(11)C]PHNO and reconstructed with Q.Clear with ÎČ < 400, which is the value used for clinical [(18)F]FDG whole-body studies, demonstrate the lowest bias versus the typical iterative reconstruction method OSEM. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s13550-022-00883-1

    Criteria for the diagnosis of corticobasal degeneration

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    Current criteria for the clinical diagnosis of pathologically confirmed corticobasal degeneration (CBD) no longer reflect the expanding understanding of this disease and its clinicopathologic correlations. An international consortium of behavioral neurology, neuropsychology, and movement disorders specialists developed new criteria based on consensus and a systematic literature review. Clinical diagnoses (early or late) were identified for 267 nonoverlapping pathologically confirmed CBD cases from published reports and brain banks. Combined with consensus, 4 CBD phenotypes emerged: corticobasal syndrome (CBS), frontal behavioral-spatial syndrome (FBS), nonfluent/agrammatic variant of primary progressive aphasia (naPPA), and progressive supranuclear palsy syndrome (PSPS). Clinical features of CBD cases were extracted from descriptions of 209 brain bank and published patients, providing a comprehensive description of CBD and correcting common misconceptions. Clinical CBD phenotypes and features were combined to create 2 sets of criteria: more specific clinical research criteria for probable CBD and broader criteria for possible CBD that are more inclusive but have a higher chance to detect other tau-based pathologies. Probable CBD criteria require insidious onset and gradual progression for at least 1 year, age at onset ≄50 years, no similar family history or known tau mutations, and a clinical phenotype of probable CBS or either FBS or naPPA with at least 1 CBS feature. The possible CBD category uses similar criteria but has no restrictions on age or family history, allows tau mutations, permits less rigorous phenotype fulfillment, and includes a PSPS phenotype. Future validation and refinement of the proposed criteria are needed

    "After my husband's circumcision, I know that I am safe from diseases": Women's Attitudes and Risk Perceptions Towards Male Circumcision in Iringa, Tanzania.

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    While male circumcision reduces the risk of female-to-male HIV transmission and certain sexually transmitted infections (STIs), there is little evidence that circumcision provides women with direct protection against HIV. This study used qualitative methods to assess women's perceptions of male circumcision in Iringa, Tanzania. Women in this study had strong preferences for circumcised men because of the low risk perception of HIV with circumcised men, social norms favoring circumcised men, and perceived increased sexual desirability of circumcised men. The health benefits of male circumcision were generally overstated; many respondents falsely believed that women are also directly protected against HIV and that the risk of all STIs is greatly reduced or eliminated in circumcised men. Efforts to engage women about the risks and limitations of male circumcision, in addition to the benefits, should be expanded so that women can accurately assess their risk of HIV or STIs during sexual intercourse with circumcised men

    Contemporary management of acute mesenteric ischemia: Factors associated with survival

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    AbstractPurpose: Acute mesenteric ischemia (AMI) is a morbid condition with a difficult diagnosis and a high rate of complications, which is associated with a high mortality rate. For the evaluation of the results of current management and the examination of factors associated with survival, we reviewed our experience. Methods: The clinical data of all the patients who underwent operation for AMI between January 1, 1990, and December 31, 1999, were retrospectively reviewed, clinical outcome was recorded, and factors associated with survival rate were analyzed. Results: Fifty-eight patients (22 men and 36 women; mean age, 67 years; age range, 35 to 96 years) underwent study. The cause of AMI was embolism in 16 patients (28%), thrombosis in 37 patients (64%), and nonocclusive mesenteric ischemia (NMI) in five patients (8.6%). Abdominal pain was the most frequent presenting symptom (95%). Twenty-five patients (43%) had previous symptoms of chronic mesenteric ischemia. All the patients underwent abdominal exploration, preceded with arteriography in 47 (81%) and with endovascular treatment in eight. Open mesenteric revascularization was performed in 43 patients (bypass grafting, n = 22; thromboembolectomy, n = 19; patch angioplasty, n = 11; endarterectomy, n = 5; reimplantation, n = 2). Thirty-one patients (53%) needed bowel resection at the first operation. Twenty-three patients underwent second-look procedures, 11 patients underwent bowel resections (repeat resection, n = 9), and three patients underwent exploration only. The 30-day mortality rate was 32%. The rate was 31% in patients with embolism, 32% in patients with thrombosis, and 80% in patients with NMI. Multiorgan failure (n = 18 patients) was the most frequent cause of death. The cumulative survival rates at 90 days, at 1 year, and at 3 years were 59%, 43%, and 32%, respectively, which was lower than the rate of a Midwestern white control population (P <.001). Six of the 16 late deaths (38%) occurred because of complications of mesenteric ischemia. Age less than 60 years (P <.003) and bowel resection (P =.03) were associated with improved survival rates. Conclusion: The contemporary management of AMI with revascularization with open surgical techniques, resection of nonviable bowel, and liberal use of second-look procedures results in the early survival of two thirds of the patients with embolism and thrombosis. Older patients, those who did not undergo bowel resection, and those with NMI have the highest mortality rates. The long-term survival rate remains dismal. Timely revascularization in patients who are symptomatic with chronic mesenteric ischemia should be considered to decrease the high mortality rate of AMI. (J Vasc Surg 2002;35:445-52.
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